Биомаркеры оптической когерентной томографии-ангиографии как индикаторы сердечной недостаточности (литературный обзор)
Ключевые слова:
оптическая когерентная томография, ангиография, микроциркуляция, сетчатка, хроническая сердечная недостаточность, биомаркерАннотация
Микрососудистая сеть сетчатки глаза уникальна тем, что ее можно неинвазивно и напрямую визуализировать и количественно оценивать. С появлением оптической когерентной томографии-ангиографии (ОКТ-А), нового инновационного метода исследования, интерес многих ученых к изучению биомаркеров значительно возрос. Этот метод позволяет более точно и эффективно выявлять различные изменения в организме. Целью данного обзора является анализ текущих исследований, посвященных применению биомаркеров, полученных с помощью ОКТ-А, в контексте сердечной недостаточности. В данном обзоре мы описали некоторые современные исследования с помощью этого метода и выделили основные биомаркеры сердечно-сосудистой патологии, такие как: уменьшение стандартного сосудистого диаметра (SVD), уменьшение диаметра венул (DVD), фовеолярная аваскулярная зона (FAZ) в поверхностном капиллярном сплетении (SCP), а именно их снижение, увеличение и корреляции между собой, наблюдаемые в макулярной и периферической зоне, которые могут служить предикторами системных нарушений, таких как хроническая сердечная недостаточность.
Библиографические ссылки
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